Kinase Inhibitors

Protein Control Ligand
Pathway Inhibitors
- Enzyme Inhibitors
- Protein Inhibitors
- Transporter Inhibitors
  - ATPases
- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
- AChE
- Peptidase
- Autophagy
- Toll-Like Receptor (TLR)
Function Modulators
- Potentiators
- Allosteric
- Votage-Gated Ion Channel Blockers
- Major Facilitator Superfamily (MFS) Transporters
- Ligand-Gated Ion Channels
- Aquaporins
- Chlorine Channels
- Connexins and Pannexins
- KCC2 - K-Cl co-transporter
- ADC cytotoxin
- ADC Linker
- CFTR
- CCK
- Monoamine Transporter
- Proton pump
Activators
- Receptor Activators
- Inducer
- Openers
- Potassium Channel
G Protein-Coupled Receptor Ligands
- 5HT Receptors
- Adrenoceptor
- Angiotensin Receptor
- Cannabinoid Receptors
- CCK Receptors
- DA Receptors
- EAA Receptors
- Ghrelin Receptors
- GABA Receptors
- Histamine Receptors
- Leukotriene Receptors
- Metabotropic Glutamate Receptors
- Motilin Receptors
- Muscarinic Receptor
- Neuropeptide Receptors
- Opioid Receptors
- Orexin Receptors
- Orphan Receptors
- Prostanoid Receptors
- Proteinase-Activated Receptors
- Purinergic Receptors
- Ryanodine receptor
- Sigma Receptors
- Thrombin Receptor
- Vaniloid Receptor
- VIP and PACAP Receptors
- Neurotensin Receptors
- Urotensin Receptor
- Imidazoline receptor
- SMO Receptors
- Apelin Receptor
- β-arrestin/β2-adaptin
- KDM4
- Glucocorticoid Receptor
- Laminin Receptor
- AHR
- Amylin Receptor
- Bombesin Receptor
- Bradykinin Receptor
- CFTR
- CGRP Receptor
- CRFR
- Endothelin Receptor
- Ephrin Receptor
- Farnesoid X receptor (FXR)
- Glucagon Receptor
Nuclear Receptor Ligands
- Retinoic Acid, X and Orphans Receptors
- Rev-Erb Receptors
- Hepatocyte Nuclear Factors Receptors
- COUP-TF Like Receptors
- Growth Factors Receptors
- Steroid Hormone Receptors
- DAX-Like Receptors
- Vitamin Related Receptors
- PPARs
- DNA Polymerase
- CRFR
- NOD
- RAAS
GDNF Receptors
TNF Receptors
Transcription Factors
Chemokines
- CXCR-2
- CXCR-3
- CXCR-4
- CXCR-7
Cytokine Receptors
- IL Receptors
- Interferon Receptors
- Integrins
- Toll-Like Receptors
- NOD-Like Receptors
Biomarkers and Buffer Solutions
- Universal DNA Markers
- Biological Buffers
- Biomarker
Molecular Probes
- Fluorescence Probes
- Chelating Agents
- Luminescent Probes
- Optical Probes
Stem Cell Research
- Reporter of Gene Expression
- CiPSC Cocktail
  - TSPC - CiPSC Cocktail
  - VC6TF - CiPSC Cocktail
- Complement System
Alzheimer's Disease
Apoptosis
Cancer Research
Epigenetics
Metabolites
PET/SPECT Imaging Precursors
Customized Screening Library
- Target Diversified Drug Like Small Molecule Library
- Target Focused Small Drug Like Molecule Library
Ultra Pure Pharmacological Standard
Tissue Microarray (TMA)
- Bladder
- Brain
- Breast
- Cervix
- Colon
- Digestive Sytem
- Esophagus
- Glucose Test Strips
- Kidney
- Large Intestine
- Liver
- Lung
- Lymphoma
- Multiple Organ
- Multiple Organ IFetus)
- Pancreas
- Prostate
- Rectum
- Reproductive System
- Stomach
- Thyroid
- Urological Sytem
Proteins and Antibodies
- Proteins and Enzymes
  - Cytokines and Chemokines
- Antibodies and Kits
  - RABBIT POLYCLONAL
  - RABBIT MONOCLONAL
- Protein Digestion Sufactant
- Cell Culture
Primary Cells
ELISA KIT
Natural Products
Lab Equipments
Humanized Mice for PDX Platform
Rare Chemicals
Custom Synthesis
Antibacterial
Antifungal
Antioxidant
Antiviral
Molecular Glues
PROTAC Linker
SARS-CoV

View larger

BI 6727

Cat No: AOB87138

Condition

CAS No:755038-65-4

Chemical Name:Volasertib

More details

Print Quotation

Molarity Calculation Cart^®

HOW TO ORDER

Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	100	$9.45	Total: $945.00
1	50	$10.92	Total: $546.00
1	25	$12.81	Total: $320.25
1	10	$15.12	Total: $151.20
1	5	$17.85	Total: $89.25

Data sheet

Molecular Formula	C34H50N8O3
Molecular Weight	618.81
CAS Numbers	755038-65-4
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO and Alcohol
Purity	99% (HPLC)
Synonym	BI6727, BI-6727, BI 6727, VolasertibIUPAC/Chemical Name:InChi Key: N-((1s,4S)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamideInChi Code: InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26+,28-/m1/s1SMILES Code:
IUPAC/Chemical Name	N-((1s,4S)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide
InChl Key	SXNJFOWDRLKDSF-FULLSBAXSA-N
InChl Code	InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26+,28-/m1/s1
SMILES Code	O=C(N[C@H]1CC[C@@H](N2CCN(CC3CC3)CC2)CC1)C4=CC=C(NC(N=C5N(C(C)C)[C@@H]6CC)=NC=C5N(C)C6=O)C(OC)=C4
References	1) Stadler WM, et al. An open-label, single-arm, phase 2 trial of the polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer. Cancer. 2013 Dec 11. doi: 10.1002/cncr.28519. [Epub ahead of print] PubMed PMID: 24339028.