Kinase Inhibitors

Protein Control Ligand
Pathway Inhibitors
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Function Modulators
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Activators
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G Protein-Coupled Receptor Ligands
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- Imidazoline receptor
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- Apelin Receptor
- β-arrestin/β2-adaptin
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- Glucocorticoid Receptor
- Laminin Receptor
Nuclear Receptor Ligands
- Retinoic Acid, X and Orphans Receptors
- Rev-Erb Receptors
- Hepatocyte Nuclear Factors Receptors
- COUP-TF Like Receptors
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GDNF Receptors
TNF Receptors
Transcription Factors
Chemokines
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Cytokine Receptors
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Biomarkers and Buffer Solutions
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Molecular Probes
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Stem Cell Research
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  - TSPC - CiPSC Cocktail
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Alzheimer's Disease
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PET/SPECT Imaging Precursors
Customized Screening Library
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Ultra Pure Pharmacological Standard
Tissue Microarray (TMA)
- Bladder
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- Multiple Organ IFetus)
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Proteins and Antibodies
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  - RABBIT POLYCLONAL
  - RABBIT MONOCLONAL
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Humanized Mice for PDX Platform
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BI 6727

Cat No: AOB87138

Condition

CAS No:755038-65-4

Chemical Name:Volasertib

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	100	$9.45	Total: $945.00
1	50	$10.92	Total: $546.00
1	25	$12.81	Total: $320.25
1	10	$15.12	Total: $151.20
1	5	$17.85	Total: $89.25

Data sheet

Molecular Formula	C34H50N8O3
Molecular Weight	618.81
CAS Numbers	755038-65-4
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO and Alcohol
Purity	99% (HPLC)
Synonym	BI6727, BI-6727, BI 6727, VolasertibIUPAC/Chemical Name:InChi Key: N-((1s,4S)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamideInChi Code: InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26+,28-/m1/s1SMILES Code:
IUPAC/Chemical Name	N-((1s,4S)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide
InChl Key	SXNJFOWDRLKDSF-FULLSBAXSA-N
InChl Code	InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26+,28-/m1/s1
SMILES Code	O=C(N[C@H]1CC[C@@H](N2CCN(CC3CC3)CC2)CC1)C4=CC=C(NC(N=C5N(C(C)C)[C@@H]6CC)=NC=C5N(C)C6=O)C(OC)=C4
References	1) Stadler WM, et al. An open-label, single-arm, phase 2 trial of the polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer. Cancer. 2013 Dec 11. doi: 10.1002/cncr.28519. [Epub ahead of print] PubMed PMID: 24339028.