Pathway Inhibitors

GB1107 View larger

GB1107

AOB17683

CAS: 1978336-61-6

Chemical Name: 3,4-Dichlorophenyl 3-deoxy-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside

AOBIOUS launched this product in 2019

CITATIONS - Publications That Use AOBIOUS Product

1) Mol Med Rep. 2021 Oct; 24(4): 685.

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC20H16Cl2F3N3O4S
Molecular Weight522.32
CAS Numbers1978336-61-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Water
Purity 99% (HPLC)
SynonymGB1107; GB-1107; GB 1107
IUPAC/Chemical Name3,4-dichlorophenyl 3-deoxy-3-[4(3,4,5-trifluorophenyl)-1H-1,2,3- triazol-1-yl]-1-thio-α-D-galactopyranoside
InChl KeyCSGJIUAIYDKFPC-DABHTEOTSA-N
InChl Code InChI=1S/C20H16Cl2F3N3O4S/c21-10-2-1-9(5-11(10)22)33-20-19(31)17(18(30)15(7-29)32-20)28-6-14(26-27-28)8-3-12(23)16(25)13(24)4-8/h1-6,15,17-20,29-31H,7H2/t15-,17+,18+,19-,20-/m1/s1
SMILES CodeO[C@H]([C@@H](N1N=NC(C2=CC(F)=C(F)C(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@H]3SC4=CC=C(Cl)C(Cl)=C4
ReferencesVuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC. An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade. Cancer Res. 2019 Apr 1;79(7):1480-1492

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Novel galectin-3 inhibitor, reducing lung adenocarcinoma growth and blocking metastasis

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