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AOB17683
CAS: 1978336-61-6
Chemical Name: 3,4-Dichlorophenyl 3-deoxy-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside
AOBIOUS launched this product in 2019
CITATIONS - Publications That Use AOBIOUS Product
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Availability date:
Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $13.95 | Total: $1,395.00 |
1 | 50 | $16.12 | Total: $806.00 |
1 | 25 | $18.91 | Total: $472.75 |
1 | 10 | $22.32 | Total: $223.20 |
1 | 5 | $26.35 | Total: $131.75 |
Molecular Formula | C20H16Cl2F3N3O4S |
Molecular Weight | 522.32 |
CAS Numbers | 1978336-61-6 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO and Water |
Purity | 99% (HPLC) |
Synonym | GB1107; GB-1107; GB 1107 |
IUPAC/Chemical Name | 3,4-dichlorophenyl 3-deoxy-3-[4(3,4,5-trifluorophenyl)-1H-1,2,3- triazol-1-yl]-1-thio-α-D-galactopyranoside |
InChl Key | CSGJIUAIYDKFPC-DABHTEOTSA-N |
InChl Code | InChI=1S/C20H16Cl2F3N3O4S/c21-10-2-1-9(5-11(10)22)33-20-19(31)17(18(30)15(7-29)32-20)28-6-14(26-27-28)8-3-12(23)16(25)13(24)4-8/h1-6,15,17-20,29-31H,7H2/t15-,17+,18+,19-,20-/m1/s1 |
SMILES Code | O[C@H]([C@@H](N1N=NC(C2=CC(F)=C(F)C(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@H]3SC4=CC=C(Cl)C(Cl)=C4 |
References | Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC. An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade. Cancer Res. 2019 Apr 1;79(7):1480-1492 |
Novel galectin-3 inhibitor, reducing lung adenocarcinoma growth and blocking metastasis