Pathway Inhibitors

BR103354 View larger

BR103354

AOB14444

CAS: 2505339-87-5

 

Chemical Name: (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-2-(4-cyanobenzyl)thiazole-4-carboxamide

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC19H15F2N5O2S
Molecular Weight415.4188
CAS Numbers505339-87-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBR103354; BR 103354; BR-103354;
IUPAC/Chemical Name(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-2-(4-cyanobenzyl)thiazole-4-carboxamide
InChl KeyPRKFSEKNKYVALC-AWEZNQCLSA-N
InChl CodeInChI=1S/C19H15F2N5O2S/c20-19(21)6-14(8-23)26(11-19)17(27)9-24-18(28)15-10-29-16(25-15)5-12-1-3-13(7-22)4-2-12/h1-4,10,14H,5-6,9,11H2,(H,24,28)/t14-/m0/s1
SMILES CodeO=C(C1=CSC(CC2=CC=C(C#N)C=C2)=N1)NCC(N3[C@H](C#N)CC(F)(F)C3)=O
References1) Cho JM, Yang EH, Quan W, Nam EH, Cheon HG. Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti- steatotic effects. Sci Rep. 2020 Dec 4;10(1):21280. doi: 10.1038/s41598-020-77978-z. PMID: 33277568; PMCID: PMC7718273.

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Novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects

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