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AOB8812
CAS No: 86445-22-9
Chemical Name: 4-(2,4-dimethylphenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid
AOBIOUS launched this product in 2018
CITATIONS - Publications That Use AOBIOUS Product
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Availability date:
Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $4.05 | Total: $405.00 |
1 | 50 | $4.68 | Total: $234.00 |
1 | 25 | $5.49 | Total: $137.25 |
1 | 10 | $6.48 | Total: $64.80 |
1 | 5 | $7.65 | Total: $38.25 |
Molecular Formula | C20H19NO3 |
Molecular Weight | 321.38 |
CAS Numbers | 86445-22-9 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
InChl Key | HGUYAIJBXSQXGV-UHFFFAOYSA-N |
Potent TIR1 antagonist, blocking the formation of the TIR1-IAA-Aux/IAA complex and so inhibiting auxin-responsive gene expression
References:
1) Smékalová V, Luptovčiak I, Komis G, Šamajová O, Ovečka M, Doskočilová A, Takáč T, Vadovič P, Novák O, Pechan T, Ziemann A, Košútová P, Šamaj J. Involvement of YODA and mitogen activated protein kinase 6 in Arabidopsis post-embryogenic root development through auxin up-regulation and cell division plane orientation. New Phytol. 2014 Sep;203(4):1175-93. doi: 10.1111/nph.12880. Epub 2014 Jun 13. PubMed PMID: 24923680; PubMed Central PMCID: PMC4414326.
2) Hayashi K, Neve J, Hirose M, Kuboki A, Shimada Y, Kepinski S, Nozaki H. Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex. ACS Chem Biol. 2012 Mar 16;7(3):590-8. doi: 10.1021/cb200404c. Epub 2012 Jan 24. PubMed PMID: 22234040.