Stem Cell Research

Auxinole View larger

Auxinole

AOB8812

CAS No: 86445-22-9

Chemical Name: 4-(2,4-dimethylphenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid

AOBIOUS launched this product in 2018

CITATIONS - Publications That Use AOBIOUS Product

1) Nucleic Acids Res. 2021 Jun 21; 49(11): 6249–6266.

2) eLife. 2021; 10: e66493.

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$9.00

$9.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.05 Total: $405.00
150 $4.68 Total: $234.00
125 $5.49 Total: $137.25
110 $6.48 Total: $64.80
15 $7.65 Total: $38.25

Data sheet

Molecular FormulaC20H19NO3
Molecular Weight321.38
CAS Numbers86445-22-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
InChl KeyHGUYAIJBXSQXGV-UHFFFAOYSA-N

More info

Potent TIR1 antagonist, blocking the formation of the TIR1-IAA-Aux/IAA complex and so inhibiting auxin-responsive gene expression

References:

1) Smékalová V, Luptovčiak I, Komis G, Šamajová O, Ovečka M, Doskočilová A, Takáč T, Vadovič P, Novák O, Pechan T, Ziemann A, Košútová P, Šamaj J. Involvement of YODA and mitogen activated protein kinase 6 in Arabidopsis post-embryogenic root development through auxin up-regulation and cell division plane orientation. New Phytol. 2014 Sep;203(4):1175-93. doi: 10.1111/nph.12880. Epub 2014 Jun 13. PubMed PMID: 24923680; PubMed Central PMCID: PMC4414326.

2) Hayashi K, Neve J, Hirose M, Kuboki A, Shimada Y, Kepinski S, Nozaki H. Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex. ACS Chem Biol. 2012 Mar 16;7(3):590-8. doi: 10.1021/cb200404c. Epub 2012 Jan 24. PubMed PMID: 22234040.

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