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AOB0156
CAS No: 350509-48-7
Chemical Name: ES2; 3-Fluorobenzoic acid [(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $5.85 | Total: $585.00 |
1 | 50 | $6.76 | Total: $338.00 |
1 | 25 | $7.93 | Total: $198.25 |
1 | 10 | $9.36 | Total: $93.60 |
1 | 5 | $11.05 | Total: $55.25 |
Molecular Formula | C15H12FIN2O3 |
Molecular Weight | 414.17 |
CAS Numbers | 350509-48-7 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | ES2; Endosidin2; Endosidin-2 |
IUPAC/Chemical Name | 3-Fluoro-benzoic acid, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide |
InChl Key | UIADDCURKKFTFW-QGMBQPNBSA-N |
InChl Code | InChI=1S/C15H12FIN2O3/c1-22-13-6-9(5-12(17)14(13)20)8-18-19-15(21)10-3-2-4-11(16)7-10/h2-8,20H,1H3,(H,19,21)/b18-8+ |
SMILES Code | FC1=CC(C(N/N=C/C2=CC(I)=C(O)C(OC)=C2)=O)=CC=C1 |
References | 1) Zhang, C., Brown, M.Q., van de Ven, W., et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc. Natl. Acad. Sci. USA 113(1), E41-E50 (2016). |
Novel inhibitor of exocytosis and endosomal recycling in both plant and human cells, binding to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex, enhancing plant vacuolar trafficking