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PD144723

AOB0865

CAS No: 148553-50-8

Chemical Name: Lyrica; 3-Isobutyl GABA; CI-1008; (S)-3-(Aminomethyl)-5-methylhexanoic acid

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Discontinued Product : Pregabalin (Cat. No. AOB0865) has been withdrawn from sale for commercial reasons.

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Data sheet

Molecular FormulaC8H17NO2
Molecular Weight159.23
CAS Numbers148553-50-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymLyrica; 3-Isobutyl GABA; CI-1008; Pregabalin
IUPAC/Chemical Name (S)-3-(Aminomethyl)-5-methylhexanoic acid
InChl KeyAYXYPKUFHZROOJ-ZETCQYMHSA-N
SMILES CodeCC(C)C[C@H](CN)CC(O)=O
References1) Field et al (2001) Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity. Br.J.Pharmacol. 132 1 PMID: 11156553

2) Kumar et al (2010) Evidence that prega. reduces neuropathic pain by inhibiting the spinal release of glutamate. J.Neurochem. 113 552 PMID: 20132471

3) Arain (2009) Pregabalin in the management of partial epilepsy. Neuropsych.Dis.Treat. 5 407
PubChem ID5486971

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GABA analog/ligand at α2δ subunit of voltage-dependent Ca2+ channels

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