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View larger Ro 28-2653
AOB2296
CAS No: 261956-22-3
Chemical Name: 5-Biphenyl-4-yl-5-[4-(-nitro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Data sheet
| Molecular Formula | C26H23N5O5 |
| Molecular Weight | 485.49 |
| CAS Numbers | 261956-22-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Ro 28-2653; Ro 28 2653; Ro 282653; Ro-28-2653; Ro282653 |
| IUPAC/Chemical Name | 5-([1,1'-biphenyl]-4-yl)-5-(4-(4-nitrophenyl)piperazin-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione |
| InChl Key | NJKTYSXXGARILV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C26H23N5O5/c32-23-26(24(33)28-25(34)27-23,20-8-6-19(7-9-20)18-4-2-1-3-5-18)30-16-14-29(15-17-30)21-10-12-22(13-11-21)31(35)36/h1-13H,14-17H2,(H2,27,28,32,33,34) |
| SMILES Code | O=C1NC(C(C2=CC=C(C3=CC=CC=C3)C=C2)(N4CCN(C5=CC=C([N+]([O-])=O)C=C5)CC4)C(N1)=O)=O |
| References | Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol. 2008 Jan 15;75(2):346-59. Epub 2007 Jul 7. Review. PubMed PMID: 17678629; PubMed Central PMCID: PMC2254136 |
More info
Novel inhibitor of matrix-metalloproteinases (MMPs) with high selectivity for MMP2, MMP9 and membrane type 1-MMP
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