Protein Inhibitors

DDD86481 bis-TFA salt View larger

DDD86481 bis-TFA salt

AOB12300

CAS: N/A

Chemical Name: 2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide bis-TFA salt

More details

Molarity Calculation Cart®

HOW TO ORDER

$59.50

$59.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.78 Total: $2,677.50
150 $30.94 Total: $1,547.00
125 $36.30 Total: $907.38
110 $42.84 Total: $428.40
15 $50.58 Total: $252.88

Data sheet

Molecular FormulaC28H32Cl2F6N6O6S
Molecular Weight765.55
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
SynonymDDD86481; DDD 86481; DDD-86481
IUPAC/Chemical Name2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide bis-TFA salt
SMILES Code
References1) Liu N, Tu J, Dong G, Wang Y, Sheng C. Emerging New Targets for the Treatment of Resistant Fungal Infections. J Med Chem. 2018 Jan 16. doi: 10.1021/acs.jmedchem.7b01413. [Epub ahead of print] PubMed PMID: 29294275.

2) Fang, W.; Robinson, D. A.; Raimi, O. G.; Blair, D. E.; Harrison, J. R.; Lockhart, D. E.; Torrie, L. S.; Ruda, G. F.; Wyatt, P. G.; Gilbert, I. H.; van Aalten, D. M. N-myristoyltransferase is a cell wall target in aspergillus fumigatus. ACS Chem. Biol. 2015, 10, 1425−1434.

More info

Novel potent AfNMT inhibitor, potently inhibiting the NMT mutant and being fungicidal under repressed nmt expression

Customers who bought this product also bought: