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Syrosingopine (Su 3118)
AOB5345
CAS No:84-36-6
Chemical Name: (3β,16β,17α,18β,20α)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-yohimban-16-carboxylic acid methyl ester, Methyl reserpate ester of syringic acid ethyl carbonate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $11.25 | Total: $1,125.00 |
| 1 | 50 | $13.00 | Total: $650.00 |
| 1 | 25 | $15.25 | Total: $381.25 |
| 1 | 10 | $18.00 | Total: $180.00 |
| 1 | 5 | $21.25 | Total: $106.25 |
Data sheet
| Molecular Formula | C35H42N2O11 |
| Molecular Weight | 666.71 |
| CAS Numbers | 84-36-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Syrosingopine; HF-41T; SU 3118 |
| IUPAC/Chemical Name | 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI) |
| InChl Key | ZCDNRPPFBQDQHR-SSYATKPKSA-N |
| InChl Code | InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1 |
| SMILES Code | [H][C@@]12C(NC3=C4C=CC(OC)=C3)=C4CCN1C[C@]5(C[C@@H](OC(C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)=O)[C@H](OC)[C@@H](C(OC)=O)[C@]5(C2)[H])[H] |
| References | 1) Palfai T, Walsh TJ. Comparison of the long-term cumulative effects of reserpine and syrosingopine on general activity. Pharmacol Biochem Behav. 1979 Nov;11(5):585-7. PubMed PMID: 43517. 2) Pham-Huu-Chanh, De Schaepdryver AF. On the pharmacology of syrosingopine and reserpine. Arch Int Pharmacodyn Ther. 1965 Sep;157(1):207-13. PubMed PMID: 4380062. 3) CALESNICK B. Reduced sedative effect of a newly synthesized reserpine derivative (syrosingopine): clinical appraisal in primary hypertension. J Am Geriatr Soc. 1959 Aug;7(8):648-55. PubMed PMID: 13672741. |
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an antihypertensive drug
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