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View larger AOB5579
CAS No:144875-48-9
498 Items
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
| Molecular Formula | C17H22N4O2 |
| Molecular Weight | 314.38 |
| CAS Numbers | 144875-48-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | R-848; R 848; R848; S 28463; S-28463; S28463; VML-600; VML600; VML 600; Resiquimod. |
| IUPAC/Chemical Name | 1-(4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol. |
| InChl Key | BXNMTOQRYBFHNZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19) |
| SMILES Code | CC(O)(C)CN1C(COCC)=NC2=C1C3=CC=CC=C3N=C2N |
| References | 1) Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32. 2) Brugnolo F, et al. The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells. J Allergy Clin Immunol. 2003 Feb;111(2):380-8. |
A potent synthetic agonist of TLR7/TLR8 that possesses antiviral and antitumoral activities. It increases the levels of cytokines such as TNF-α, IL-6 and IFN-α.