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Capzimin
AOB8855
CAS No: 2084867-65-0
Chemical Name: CZM; 8-Mercapto-N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $23.85 | Total: $2,385.00 |
| 1 | 50 | $27.56 | Total: $1,378.00 |
| 1 | 25 | $32.33 | Total: $808.25 |
| 1 | 10 | $38.16 | Total: $381.60 |
| 1 | 5 | $45.05 | Total: $225.25 |
Data sheet
| Molecular Formula | C15H13N3OS2 |
| Molecular Weight | 315.41 |
| CAS Numbers | 2084867-65-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
| IUPAC/Chemical Name | 8-Mercapto-N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide |
| InChl Key | MYNGHZGMRXNEEH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H13N3OS2/c19-15(17-5-4-13-16-6-7-21-13)11-8-10-2-1-3-12(20)14(10)18-9-11/h1-3,6-9,20H,4-5H2,(H,17,19) |
| SMILES Code | O=C(C1=CC2=CC=CC(S)=C2N=C1)NCCC3=NC=CS3 |
| References | Li J, Yakushi T, Parlati F, Mackinnon AL, Perez C, Ma Y, Carter KP, Colayco S, Magnuson G, Brown B, Nguyen K, Vasile S, Suyama E, Smith LH, Sergienko E, Pinkerton AB, Chung TDY, Palmer AE, Pass I, Hess S, Cohen SM, Deshaies RJ. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017 May;13(5):486-493. doi: 10.1038/nchembio.2326. Epub 2017 Feb 28. PubMed PMID: 28244987. |
More info
Novel potent and specific inhibitor of proteasome isopeptidase Rpn11
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