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AOB8813
CAS: 2232180-74-2
Chemical Name: 3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-yl]-7-methoxy-quinoline
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $17.55 | Total: $1,755.00 |
1 | 50 | $20.28 | Total: $1,014.00 |
1 | 25 | $23.79 | Total: $594.75 |
1 | 10 | $28.08 | Total: $280.80 |
1 | 5 | $33.15 | Total: $165.75 |
Molecular Formula | C18H12BrN3O2 |
Molecular Weight | 382.217 |
CAS Numbers | 2232180-74-2 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | BT173; BT-173; BT 173;IUPAC/Chemical Name:InChi Key:InChi Code: SMILES Code: |
IUPAC/Chemical Name | 3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-yl]-7-methoxy-quinoline |
InChl Key | IZEKVHBNUXXZFE-UHFFFAOYSA-N |
InChl Code | InChI=1S/C18H12BrN3O2/c1-23-15-7-4-12-8-13(10-20-16(12)9-15)18-21-17(22-24-18)11-2-5-14(19)6-3-11/h2-10H,1H3 |
SMILES Code | COC1=CC=C2C=C(C3=NC(C4=CC=C(Br)C=C4)=NO3)C=NC2=C1 |
References | 1) Liu R, Das B, Xiao W, Li Z, Li H, Lee K, He JC. A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-β1/Smad3 Pathway. J Am Soc Nephrol. 2017 Feb 20. pii: ASN.2016080841. doi: 10.1681/ASN.2016080841. [Epub ahead of print] PubMed PMID: 28220029. |
Novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway