Nuclease

DNA2-IN-C5 View larger

NSC15765 (DNA2-IN-C5)

AOB9082

CAS No: 35973-25-2

 

Chemical Name: NSC15765; 4-Hydroxy-8-nitroquinoline-3-carboxylic acid; 8-Nitro-4-oxo-1H-quinoline-3-carboxylic acid

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $16.65 Total: $1,665.00
50 $19.24 Total: $962.00
25 $22.57 Total: $564.25
10 $26.64 Total: $266.40
5 $31.45 Total: $157.25

Data sheet

Molecular FormulaC10H6N2O5
Molecular Weight234.17
CAS Numbers35973-25-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymDNA2-IN-C5; DNA2 IN C5; DNA2INC5; NSC15765; NSC-15765; NSC 15765
IUPAC/Chemical Name8-Nitro-4-oxo-1H-quinoline-3-carboxylic acid
InChl KeyBMIZBCVEHSUUNO-UHFFFAOYSA-N
InChl CodeInChI=1S/C10H6N2O5/c13-9-5-2-1-3-7(12(16)17)8(5)11-4-6(9)10(14)15/h1-4H,(H,11,13)(H,14,15)
SMILES CodeO=C(C1=CNC2=C(C=CC=C2[N+]([O-])=O)C1=O)O
ReferencesLiu W, Zhou M, Li Z, Li H, Polaczek P, Dai H, Wu Q, Liu C, Karanja KK, Popuri V, Shan SO, Schlacher K, Zheng L, Campbell JL, Shen B. A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy. EBioMedicine. 2016 Apr;6:73-86. doi: 10.1016/j.ebiom.2016.02.043. Epub 2016 Mar 10. PubMed PMID: 27211550; PubMed Central PMCID: PMC4856754

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Novel specific inhibitor of DNA2 nuclease activity

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