Pathway Inhibitors

Arimoclomol View larger

Arimoclomol

AOB5425

CAS: 289893-25-0

Chemical Name: BRX220; (3Z)-N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC14H20ClN3O3
Molecular Weight313.78
CAS Numbers289893-25-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBRX220
IUPAC/Chemical Name(3Z)-N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride
InChl KeySGEIEGAXKLMUIZ-CYBMUJFWSA-N
InChl CodeInChI=1S/C14H20ClN3O3/c15-14(12-5-4-8-18(20)9-12)16-21-11-13(19)10-17-6-2-1-3-7-17/h4-5,8-9,13,19H,1-3,6-7,10-11H2/t13-/m1/s1
SMILES CodeC1CCN(CC1)CC(CON=C(C2=C[N+](=CC=C2)[O-])Cl)O
References1) Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.

2) Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.

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Novel stimulator of a normal cellular protein repair pathway, activating the heat shock response and acting at Hsp70, for treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease

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