Enzyme Inhibitors

GSK620 View larger

GSK620

AOB11616

CAS: 2088410-46-0

 

Chemical Name: 1-Benzyl-N5-cyclopropyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide

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Molarity Calculation Cart®

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC18H19N3O3
Molecular Weight325.37
CAS Numbers2088410-46-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymGSK-620; GSK 620
IUPAC/Chemical Name1-Benzyl-N5-cyclopropyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide
References1) Gilan, O., et al., Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation, Science 24 Apr 2020: Vol. 368, Issue 6489, pp. 387-394 DOI: 10.1126/science.aaz8455

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Novel BD2-selective BET inhibitor in vivo tool , binding to the individual tandem bromodomains [BD1 and BD2] of BRD2, BRD3, BRD4, and BRDT

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